The structural difference in regional development between Europe and the rest of the world is linked with the history of Megapolises. As a notion, megapolis (megalopolis) comes from Isaiah Bowman’s explanation of the USA’s cities in 1942 as high-density populated great cities (Gottmann, 1957). Moreover, the notion was expanded by including the reasons for the high-density population and its outcomes to the cities. Obviously, more opportunities in work and education became the main reason for high population flows to megapolises. On the other hand, more workforce and education benefits such as innovations and technologies became profitable for governments. As a result, creating megapolises became a vital policy to gather all the capital, including human and non-human capital, at one point.